Title : Comparison of the actions of acylated and desacylated ghrelin on acid secretion in the rat stomach.

Pub. Date : 2010 Nov

PMID : 20571831






3 Functional Relationships(s)
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1 In the present study, we compared desacyl and acyl ghrelin with regard to acid secretion and histamine production in the rat stomach. Histamine ghrelin and obestatin prepropeptide Rattus norvegicus
2 CONCLUSIONS: The results indicate that acyl ghrelin stimulates gastric acid secretion via a mechanism involving activation of the vagus nerve and histamine release and synthesis and that desacyl ghrelin has no action on gastric acid secretion. Histamine ghrelin and obestatin prepropeptide Rattus norvegicus
3 Furthermore, the results demonstrate synergism between gastrin and acyl ghrelin in terms of gastric acid secretion via a mechanism involving histamine release and synthesis. Histamine ghrelin and obestatin prepropeptide Rattus norvegicus