Pub. Date : 1978 Apr
PMID : 205622
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Specific inhibition of glutamic acid decarboxylase (GAD, EC 4.1.1.15; the main enzyme involved in the synthesis of gamma-aminobutyric acid) by mercaptopropionic acid interferes with the effect of dexamethasone on both the resting and stress-induced secretion of ACTH. | gamma-Aminobutyric Acid | glutamate decarboxylase 1 | Homo sapiens |
| 2 | It is postulated that dexamethasone may, at least in part, inhibit the secretion of ACTH via the induction of GAD, thereby raising the level of gamma-aminobutyric acid in the central nervous system. | gamma-Aminobutyric Acid | glutamate decarboxylase 1 | Homo sapiens |