Title : Piceatannol induces heme oxygenase-1 expression in human mammary epithelial cells through activation of ARE-driven Nrf2 signaling.

Pub. Date : 2010 Sep 1

PMID : 20558128






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We hypothesize that an electrophilic quinone formed as a consequence of oxidation of piceatannol bearing the catechol moiety may bind directly to Kelch-like ECH-associated protein 1 (Keap1), an inhibitory protein that sequesters Nrf2 in the cytoplasm. catechol NFE2 like bZIP transcription factor 2 Homo sapiens
2 The characteristic catechol moiety of piceatannol appears to be critical for induction of Nrf2 activation and subsequent upregulation of HO-1. catechol NFE2 like bZIP transcription factor 2 Homo sapiens