Title : 17Beta-estradiol promotes TLR4-triggered proinflammatory mediator production through direct estrogen receptor alpha signaling in macrophages in vivo.

Pub. Date : 2010 Jul 15

PMID : 20554954






1 Functional Relationships(s)
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1 We show in this study that chronic E2 administration to ovariectomized mice significantly increased both cytokine (IL-1beta, IL-6, and TNF-alpha) and inducible NO synthase mRNA abundance in thioglycolate (TGC)-elicited macrophages. Thioglycolates nitric oxide synthase 2, inducible Mus musculus