Title : 3beta-hydroxysteroid dehydrogenase is a possible pharmacological target in the treatment of castration-resistant prostate cancer.

Pub. Date : 2010 Aug

PMID : 20534728






1 Functional Relationships(s)
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1 We hypothesized that activation of AR in prostate cancer by DHEA and A5diol requires their conversion via 3betaHSD to androstenedione and testosterone, respectively. Androstenedione androgen receptor Homo sapiens