Title : RGS inhibition at G(alpha)i2 selectively potentiates 5-HT1A-mediated antidepressant effects.

Pub. Date : 2010 Jun 15

PMID : 20534514






1 Functional Relationships(s)
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1 RGS-insensitive mice were also 5-10 times more responsive to the antidepressant-like effects of the SSRI fluvoxamine and 5-HT1A-selective agonist 8-hydroxy-2-dipropylaminotetralin. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine (serotonin) receptor 1A Mus musculus