Pub. Date : 2010 Nov
PMID : 20533067
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Compared with other BPs, zoledronic acid (ZOL) has a higher affinity to bone mineral and is a stronger inhibitor of the enzyme farnesyl pyrophosphate synthase (the main target of nitrogen-containing BPs), properties that explain the prolonged effect of ZOL on bone turnover and render it a therapeutic option for JPD, similar to PDB. | Diphosphonates | farnesyl diphosphate synthase | Homo sapiens |