Title : Requirement of NOX2 and reactive oxygen species for efficient RIG-I-mediated antiviral response through regulation of MAVS expression.

Pub. Date : 2010 Jun 3

PMID : 20532218






1 Functional Relationships(s)
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1 Here, we found that NOX2 and ROS are required for the host cell to trigger an efficient RIG-I-mediated IRF-3 activation and downstream antiviral IFNbeta and IFIT1 gene expression. Reactive Oxygen Species interferon beta 1 Homo sapiens