Title : Suppression of the novel ER protein Maxer by mutant ataxin-1 in Bergman glia contributes to non-cell-autonomous toxicity.

Pub. Date : 2010 Jul 21

PMID : 20531390






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Glutamate-aspartate transporter reduction in Bergmann glia by mutant Atx1 and vulnerability of Purkinje cell to glutamate are both strengthened by Maxer knockdown in Bergmann glia, whereas Maxer overexpression rescues them. Glutamic Acid ataxin 1 Mus musculus