Title : CuZnSOD and MnSOD inhibit metabolic stress-induced necrosis and multicellular tumour spheroid growth.

Pub. Date : 2010 Jul

PMID : 20514411






1 Functional Relationships(s)
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1 We observed that CuZnSOD and MnSOD overexpression prevents metabolic stress-induced necrosis and HMGB1 release by inhibiting mitochondrial ROS and intracellular O2- production in response to glucose depletion in two dimensional cell culture. Oxygen superoxide dismutase 2 Homo sapiens