Title : Generation of Th1-polarizing dendritic cells using the TLR7/8 agonist CL075.

Pub. Date : 2010 Jul 1

PMID : 20511554






1 Functional Relationships(s)
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1 Mixtures that included the TLR7/8 agonists R848 or CL075, combined with the TLR3 agonist polyinosinic:polycytidylic acid, yielded 3-d mature DCs that secreted high levels of IL-12(p70), showed strong chemotaxis to CCR7 ligands, and had a positive costimulatory potential. polyinosinic toll like receptor 3 Homo sapiens