Title : Chronic oxidative stress sensitizes hepatocytes to death from 4-hydroxynonenal by JNK/c-Jun overactivation.

Pub. Date : 2009 Nov

PMID : 20501438






1 Functional Relationships(s)
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Protein Name
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1 GSH depletion led to overactivation of JNK/c-Jun signaling at the level of mitogen-activated protein kinase kinase 4 that induced cell death. Glutathione mitogen-activated protein kinase 8 Homo sapiens