Title : Pharmacokinetic modeling of the dosing interval dependency for the interaction between itraconazole and triazolam.

Pub. Date : 2010 Jun

PMID : 20497744






2 Functional Relationships(s)
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1 OBJECTIVE: Itraconazole is a potent inhibitor of cytochrome P450 (CYP) 3A with an elimination half-life of more than 30 hours. Itraconazole cytochrome P450 family 3 subfamily A member 4 Homo sapiens
2 Therefore, itraconazole may cause persistent CYP3A inhibition. Itraconazole cytochrome P450 family 3 subfamily A member 4 Homo sapiens