Title : RET codon 804 mutations in multiple endocrine neoplasia 2: genotype-phenotype correlations and implications in clinical management.

Pub. Date : 2011 Jan

PMID : 20497437






3 Functional Relationships(s)
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1 These mutations cause changes in either the cysteine-rich extracellular domain or, less commonly, the non-cysteine intracellular domains of the RET protein. Cysteine ret proto-oncogene Homo sapiens
2 The genotype-phenotype correlations of classical cysteine RET mutations have been the subject of several comprehensive reviews. Cysteine ret proto-oncogene Homo sapiens
3 This review summarizes the genotypic and phenotypic characteristics of RET codon 804 mutation, a prototype for the less well-defined non-cysteine RET mutations associated with MEN 2. Cysteine ret proto-oncogene Homo sapiens