Title : Arsenic trioxide alleviates airway hyperresponsiveness and eosinophilia in a murine model of asthma.

Pub. Date : 2010 Sep

PMID : 20495578






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We found that administration of As2O3 in OVA-immunized mice abrogated airway eosinophil recruitment by downregulating eotaxin expression but did not alter serum IgE or IL-5 levels in bronchoalveolar lavage fluid (BALF). Arsenic Trioxide chemokine (C-C motif) ligand 11 Mus musculus
2 In vitro data suggested that low concentrations of As2O3 could induce only a small degree of apoptosis in primary pulmonary cells but could significantly inhibit the secretion of eotaxin by these cells. Arsenic Trioxide chemokine (C-C motif) ligand 11 Mus musculus