Title : Increased responsiveness to JNK1/2 mediates the enhanced H2O2-induced stimulation of Cl-/HCO3- exchanger activity in immortalized renal proximal tubular epithelial cells from the SHR.

Pub. Date : 2010 Sep 15

PMID : 20493825






1 Functional Relationships(s)
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1 The stimulatory effect of H2O2 on the exchanger activity was blocked by SP600125 (JNK inhibitor), but not by U0126 (MEK1/2 inhibitor) or SB203580 (p38 inhibitor) in both cell lines. Hydrogen Peroxide mitogen activated protein kinase 14 Rattus norvegicus