Title : Regulation of ?-aminobutyric acid synthesis in the vertebrate nervous system.

Pub. Date : 1986

PMID : 20493058






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 The regulation of glutamic decarboxylase (GAD) activity is undoubtedly the key to the control of the steady-state concentrations of 4-aminobutyric acid (GABA) in the central nervous system. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens
2 The regulation of glutamic decarboxylase (GAD) activity is undoubtedly the key to the control of the steady-state concentrations of 4-aminobutyric acid (GABA) in the central nervous system. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens
3 The regulation of glutamic decarboxylase (GAD) activity is undoubtedly the key to the control of the steady-state concentrations of 4-aminobutyric acid (GABA) in the central nervous system. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens
4 The regulation of glutamic decarboxylase (GAD) activity is undoubtedly the key to the control of the steady-state concentrations of 4-aminobutyric acid (GABA) in the central nervous system. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens
5 Experiments are suggested that would help clarify (1) the role of GABA in GAD repression; (2) the possible phosphorylation of GAD; and (3) the existence of multiple forms of the enzyme. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens
6 However, a possible mechanism relying on the direct feedback action of GABA on GAD activity has many attractive features. gamma-Aminobutyric Acid glutamate decarboxylase 1 Homo sapiens