Pub. Date : 2010 May
PMID : 20490773
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | SP600125, an inhibitor of c-Jun NH2-terminal kinase, blocks expression of angiotensin II-induced monocyte chemoattractant protein-1 in human mesangial cells. | pyrazolanthrone | C-C motif chemokine ligand 2 | Homo sapiens |
| 2 | SP600125 also reduced MCP-1 mRNA stability: the halflife of MCP-1 mRNA was approximately 5 hours in cells treated with Ang II only, but was reduced to 2 hours when treated with a combination of Ang II and SP600125. | pyrazolanthrone | C-C motif chemokine ligand 2 | Homo sapiens |
| 3 | SP600125 also reduced MCP-1 mRNA stability: the halflife of MCP-1 mRNA was approximately 5 hours in cells treated with Ang II only, but was reduced to 2 hours when treated with a combination of Ang II and SP600125. | pyrazolanthrone | C-C motif chemokine ligand 2 | Homo sapiens |
| 4 | SP600125 also reduced MCP-1 mRNA stability: the halflife of MCP-1 mRNA was approximately 5 hours in cells treated with Ang II only, but was reduced to 2 hours when treated with a combination of Ang II and SP600125. | pyrazolanthrone | C-C motif chemokine ligand 2 | Homo sapiens |
| 5 | SP600125 also reduced MCP-1 mRNA stability: the halflife of MCP-1 mRNA was approximately 5 hours in cells treated with Ang II only, but was reduced to 2 hours when treated with a combination of Ang II and SP600125. | pyrazolanthrone | C-C motif chemokine ligand 2 | Homo sapiens |