Title : Deficiency in hepatic ATP-citrate lyase affects VLDL-triglyceride mobilization and liver fatty acid composition in mice.

Pub. Date : 2010 Sep

PMID : 20488800






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 ATP-citrate lyase (ACL) is a key lipogenic enzyme that converts citrate in the cytoplasm to acetyl-CoA, the initial precursor that yields malonyl-CoA for fatty acid biosynthesis. Acetyl Coenzyme A ATP citrate lyase Mus musculus
2 ATP-citrate lyase (ACL) is a key lipogenic enzyme that converts citrate in the cytoplasm to acetyl-CoA, the initial precursor that yields malonyl-CoA for fatty acid biosynthesis. Acetyl Coenzyme A ATP citrate lyase Mus musculus
3 Hepatic ACL abrogation markedly reduced the liver abundance of both acetyl-CoA and malonyl-CoA regardless of dietary fat intake, which was paralleled with decreases in circulating levels of triglycerides and free fatty acids. Acetyl Coenzyme A ATP citrate lyase Mus musculus