Title : Unveiling the unfolding pathway of FALS associated G37R SOD1 mutant: a computational study.

Pub. Date : 2010 Jun

PMID : 20485746






1 Functional Relationships(s)
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1 In fact it is shown that the G37R mutation, although located far away the active site, may induce subtle modification in SOD1 leading to the loosening of metal binding and to the formation of metastable intermediate states along the unfolding pathway. Metals superoxide dismutase 1 Homo sapiens