Title : Dose-dependent increase in intratesticular testosterone by very low-dose human chorionic gonadotropin in normal men with experimental gonadotropin deficiency.

Pub. Date : 2010 Aug

PMID : 20484472






3 Functional Relationships(s)
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1 CONTEXT AND OBJECTIVE: In men with infertility secondary to gonadotropin deficiency, treatment with relatively high dosages of human chorionic gonadotropin (hCG) stimulates intratesticular testosterone (IT-T) biosynthesis and spermatogenesis. Testosterone chorionic gonadotropin subunit beta 5 Homo sapiens
2 However, the minimal dose of hCG needed to stimulate IT-T and the dose-response relationship between very low doses of hCG and IT-T and serum testosterone in normal men is unknown. Testosterone chorionic gonadotropin subunit beta 5 Homo sapiens
3 Moreover, serum hCG was significantly correlated with both IT-T and serum testosterone (P<0.01). Testosterone chorionic gonadotropin subunit beta 5 Homo sapiens