Pub. Date : 2010 Aug
PMID : 20477948
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | ATP induced both activation of nuclear factor of activated T cells (NFAT) and MAPKs (p38, ERK, and JNK) through P2X7R. | Adenosine Triphosphate | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | ATP-induced mRNA expression of CXCL2 was inhibited by INCA-6 (an NFAT inhibitor), SB203580 (a p38 inhibitor), U0126 (a MEK-ERK inhibitor) and JNK inhibitor II (a JNK inhibitor). | Adenosine Triphosphate | mitogen-activated protein kinase 8 | Homo sapiens |
| 3 | ATP-induced mRNA expression of CXCL2 was inhibited by INCA-6 (an NFAT inhibitor), SB203580 (a p38 inhibitor), U0126 (a MEK-ERK inhibitor) and JNK inhibitor II (a JNK inhibitor). | Adenosine Triphosphate | mitogen-activated protein kinase 8 | Homo sapiens |
| 4 | In addition, protein kinase C inhibitors suppressed ATP-induced ERK and JNK activation, and also inhibited ATP-induced CXCL2 expression in microglia. | Adenosine Triphosphate | mitogen-activated protein kinase 8 | Homo sapiens |