Pub. Date : 2010 Apr
PMID : 20470305
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Pentoxifylline improves haemoglobin and interleukin-6 levels in chronic kidney disease. | Pentoxifylline | interleukin 6 | Homo sapiens |
| 2 | AIM: To assess whether pentoxifylline improves anaemia of chronic kidney disease (CKD) via suppression of interleukin-6 (IL-6) and improved iron mobilization. | Pentoxifylline | interleukin 6 | Homo sapiens |
| 3 | AIM: To assess whether pentoxifylline improves anaemia of chronic kidney disease (CKD) via suppression of interleukin-6 (IL-6) and improved iron mobilization. | Pentoxifylline | interleukin 6 | Homo sapiens |
| 4 | In experimental models, pentoxifylline was shown to reduce IL-6 expression. | Pentoxifylline | interleukin 6 | Homo sapiens |
| 5 | Treatment with pentoxifylline reduced circulating IL-6 (6.6 + or - 1.6 pg/mL, P < 0.01), increased transferrin saturation (20 + or - 5%, P < 0.003) and decreased serum ferritin (81 + or - 25 microg/L, P = NS). | Pentoxifylline | interleukin 6 | Homo sapiens |
| 6 | CONCLUSIONS: Pentoxifylline reduces circulating IL-6 and improves haemoglobin in non-inflammatory moderate to severe CKD. | Pentoxifylline | interleukin 6 | Homo sapiens |