Title : Biological and molecular mechanisms of sulfur mustard analogue-induced toxicity in JB6 and HaCaT cells: possible role of ataxia telangiectasia-mutated/ataxia telangiectasia-Rad3-related cell cycle checkpoint pathway.

Pub. Date : 2010 Jun 21

PMID : 20469912






2 Functional Relationships(s)
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1 An increase in caspase-3 activity and both caspase-3 and poly(ADP-ribose)polymerase (PARP) cleavage coinciding with CEES-caused apoptosis in both cell lines suggested the involvement of the caspase pathway. 2-chloroethyl ethyl sulfide poly(ADP-ribose) polymerase 1 Homo sapiens
2 An increase in caspase-3 activity and both caspase-3 and poly(ADP-ribose)polymerase (PARP) cleavage coinciding with CEES-caused apoptosis in both cell lines suggested the involvement of the caspase pathway. 2-chloroethyl ethyl sulfide poly(ADP-ribose) polymerase 1 Homo sapiens