Pub. Date : 2010 Jul
PMID : 20467806
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Preparation of chondroitin sulfate libraries containing disulfated disaccharide units and inhibition of thrombin by these chondroitin sulfates. | Chondroitin Sulfates | coagulation factor II, thrombin | Homo sapiens |
| 2 | We prepared CS libraries containing E unit or D unit in various proportions by in vitro enzymatic reactions using recombinant GalNAc 4-sulfate 6-O-sulfotransferase and uronosyl 2-O-sulfotransferase, and examined their inhibitory activity toward thrombin. | Chondroitin Sulfates | coagulation factor II, thrombin | Homo sapiens |
| 3 | The thrombin-catalyzed degradation of fibrinogen, a physiological substrate for thrombin, was also inhibited by the CS containing both E unit and D unit. | Chondroitin Sulfates | coagulation factor II, thrombin | Homo sapiens |
| 4 | The thrombin-catalyzed degradation of fibrinogen, a physiological substrate for thrombin, was also inhibited by the CS containing both E unit and D unit. | Chondroitin Sulfates | coagulation factor II, thrombin | Homo sapiens |