Title : 5HT-1A receptors and anxiety-like behaviours: studies in rats with constitutionally upregulated/downregulated serotonin transporter.

Pub. Date : 2010 Dec 1

PMID : 20457184






1 Functional Relationships(s)
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1 The involvement of 5HT-1A receptors in behavioural response was assessed by measuring mRNA expression in cell bodies (raphe nuclei) and projection regions (frontal cortex, hippocampus) by use of RT-PCR and in situ hybridization, and by measuring functionality of cortical 5HT-1A receptors by use of [(3)H]8-OH-DPAT radioligand binding. 8-Hydroxy-2-(di-n-propylamino)tetralin 5-hydroxytryptamine receptor 1A Rattus norvegicus