Pub. Date : 2010 Sep 6
PMID : 20452337
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Here, we searched potential AChE inhibitors from flavonoids, a group of naturally occurring compounds in plants or traditional Chinese medicines (TCM). | Flavonoids | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
2 | Twenty-one flavonoids, covered different subclasses, were tested for their potential function in inhibiting AChE activity from the brain in vitro. | Flavonoids | acetylcholinesterase (Cartwright blood group) | Homo sapiens |
3 | showed an inhibitory effect on AChE activity with the highest inhibition by over 55% and an IC(50) of 120 microM and an enzyme-flavonoid inhibition constant (K(i)) of 74 microM. | Flavonoids | acetylcholinesterase (Cartwright blood group) | Homo sapiens |