Pub. Date : 2010 Aug 15
PMID : 20451502
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Neither of these structural changes prevented cDDP from triggering the rapid degradation of hCTR1. | cddp | solute carrier family 31 member 1 | Homo sapiens |
| 2 | However, they did alter the potency of the cDDP that achieved cell entry, possibly reflecting the fact that hCTR1 may mediate the transport of cDDP both through the pore it forms in the plasma membrane and via endocytosis. | cddp | solute carrier family 31 member 1 | Homo sapiens |
| 3 | However, they did alter the potency of the cDDP that achieved cell entry, possibly reflecting the fact that hCTR1 may mediate the transport of cDDP both through the pore it forms in the plasma membrane and via endocytosis. | cddp | solute carrier family 31 member 1 | Homo sapiens |
| 4 | We conclude that cDDP interacts with hCTR1 both at (40)MXXM(45) and at sites outside the N-terminal domain that produce the conformational changes that trigger degradation. | cddp | solute carrier family 31 member 1 | Homo sapiens |