Title : Are corticosteroids efficacious for preventing or treating neutralizing antibodies in multiple sclerosis patients treated with beta-interferons? A critically appraised topic.

Pub. Date : 2010 May

PMID : 20445436






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A randomized controlled trial for patients with active disease despite IFNB therapy showed that baseline NAb titers were reduced by subsequent intravenous methylprednisolone treatment, but the incidence of NAbs was too small to assess clinical relevance. Methylprednisolone interferon beta 1 Homo sapiens
2 CONCLUSIONS: Pulse methylprednisolone therapy may reduce the risk of developing NAbs (but possibly not high-titer NAbs of clinical importance) when coadministered with newly initiated IFNB therapy. Methylprednisolone interferon beta 1 Homo sapiens