Title : Bone morphogenetic protein-2 delivered by hyaluronan-based hydrogel induces massive bone formation and healing of cranial defects in minipigs.

Pub. Date : 2010 May

PMID : 20440158






1 Functional Relationships(s)
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1 The authors have developed a hydrogel that is formed in situ by the cross-linking of multifunctional hyaluronic acid and polyvinyl alcohol derivatives mixed with hydroxyapatite nanoparticles, in the presence of BMP-2. Polyvinyl Alcohol bone morphogenetic protein 2 Homo sapiens