Title : Cytochromes P4501 (CYP1): catalytic activities and inducibility by diesel exhaust particle extract and benzo[a]pyrene in intact human lung ex vivo.

Pub. Date : 2010 Jun 29

PMID : 20435083






1 Functional Relationships(s)
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1 All three activities were substantially inhibited (>or=75%) by the CYP1 inhibitor alpha-naphthoflavone, whereas only MROD and CECOD were substantially inhibited by the CYP1A2-preferential inhibitor fluvoxamine. alpha-naphthoflavone cytochrome P450 family 1 subfamily A member 2 Homo sapiens