Title : A probasin promoter, conditionally replicating adenovirus that expresses the sodium iodide symporter (NIS) for radiovirotherapy of prostate cancer.

Pub. Date : 2010 Nov

PMID : 20428214






4 Functional Relationships(s)
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1 We have extended the use of NIS-mediated radioiodine therapy to other types of cancer, we transferred and expressed the NIS gene into prostate, colon and breast cancer cells using adenoviral vectors. Iodine-131 solute carrier family 5 member 5 Homo sapiens
2 We have extended the use of NIS-mediated radioiodine therapy to other types of cancer, we transferred and expressed the NIS gene into prostate, colon and breast cancer cells using adenoviral vectors. Iodine-131 solute carrier family 5 member 5 Homo sapiens
3 Radioiodine uptake was readily measurable in LnCaP cells infected with Ad5PB_RSV-NIS 24 h post-infection, confirming NIS expression. Iodine-131 solute carrier family 5 member 5 Homo sapiens
4 Radioiodine uptake was readily measurable in LnCaP cells infected with Ad5PB_RSV-NIS 24 h post-infection, confirming NIS expression. Iodine-131 solute carrier family 5 member 5 Homo sapiens