Title : Amphiregulin carboxy-terminal domain is required for autocrine keratinocyte growth.

Pub. Date : 2010 Aug

PMID : 20428186






1 Functional Relationships(s)
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1 TET-induced expression of AREG shRNA markedly reduced autocrine extracellular signal-regulated kinase phosphorylation, strongly inhibited autocrine KC growth with an efficiency similar to metalloproteinase and EGFR inhibitors, and induced several markers of KC differentiation, including keratins 1 and 10. Tetracycline epidermal growth factor receptor Homo sapiens