Title : (1,3)-beta-glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages.

Pub. Date : 2010 Jun 1

PMID : 20421639






2 Functional Relationships(s)
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1 This beta-glucan triggered IL-1beta release was abolished by cytochalasin D, an inhibitor of phagocytosis, demonstrating that cytosolic recognition of beta-glucans is required for IL-1beta response in human macrophages. Cytochalasin D interleukin 1 beta Homo sapiens
2 This beta-glucan triggered IL-1beta release was abolished by cytochalasin D, an inhibitor of phagocytosis, demonstrating that cytosolic recognition of beta-glucans is required for IL-1beta response in human macrophages. Cytochalasin D interleukin 1 beta Homo sapiens