Title : (1,3)-beta-glucans activate both dectin-1 and NLRP3 inflammasome in human macrophages.

Pub. Date : 2010 Jun 1

PMID : 20421639






1 Functional Relationships(s)
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1 Furthermore, our results suggest that the lysosomal cathepsin B protease, the formation of reactive oxygen species, and the efflux of potassium are needed for beta-glucan-induced NLRP3 inflammasome activation. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens