Title : Phenothiazines inhibit S100A4 function by inducing protein oligomerization.

Pub. Date : 2010 May 11

PMID : 20421509






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Phenothiazines inhibit S100A4 function by inducing protein oligomerization. Phenothiazines S100 calcium binding protein A4 Homo sapiens
2 Together these studies support a unique mode of inhibition in which phenothiazines disrupt the S100A4/myosin-IIA interaction by sequestering S100A4 via small molecule-induced oligomerization. Phenothiazines S100 calcium binding protein A4 Homo sapiens
3 Together these studies support a unique mode of inhibition in which phenothiazines disrupt the S100A4/myosin-IIA interaction by sequestering S100A4 via small molecule-induced oligomerization. Phenothiazines S100 calcium binding protein A4 Homo sapiens