Title : Synthesis and evaluation of benzoxazinone derivatives on activity of human neutrophil elastase and on hemorrhagic shock-induced lung injury in rats.

Pub. Date : 2010 Jul

PMID : 20417587






1 Functional Relationships(s)
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1 A new series of benzoxazinone analogs were designed, synthesized, and assayed to determine their effects on superoxide anion generation and neutrophil elastase (NE) release in formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)-activated human neutrophils. N-Formylmethionine Leucyl-Phenylalanine formyl peptide receptor 1 Homo sapiens