Title : Combined influence of LDLR and HMGCR sequence variation on lipid-lowering response to simvastatin.

Pub. Date : 2010 Jul

PMID : 20413733






1 Functional Relationships(s)
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1 LDLR haplotype 5 (LDLR L5) was associated with smaller simvastatin-induced reductions in low-density lipoprotein cholesterol, total cholesterol, non-high-density lipoprotein cholesterol, and apolipoprotein B (P=0.0002 to 0.03) in blacks but not whites. Simvastatin apolipoprotein B Homo sapiens