Title : Calcineurin mediates the angiotensin II-induced aldosterone synthesis in the adrenal glands by up-regulation of transcription of the CYP11B2 gene.

Pub. Date : 2010 Jul

PMID : 20413672






2 Functional Relationships(s)
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1 First, CN inhibitors, cyclosporine A (CysA) and tacrolimus (FK506) inhibited the Ang II-induced elevation of CYP11B2 mRNA level. Tacrolimus angiotensinogen Homo sapiens
2 First, CN inhibitors, cyclosporine A (CysA) and tacrolimus (FK506) inhibited the Ang II-induced elevation of CYP11B2 mRNA level. Tacrolimus angiotensinogen Homo sapiens