Title : Development and optimization of a high-throughput bioassay for TRPM7 ion channel inhibitors.

Pub. Date : 2010 Jun

PMID : 20413646






2 Functional Relationships(s)
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1 The authors developed and optimized a fluorescent dye-based bioassay measuring the fluorescence quench of fura-2 by TRPM7-mediated Mn2+ influx in HEK293 cells that stably overexpress TRPM7. Fura-2 transient receptor potential cation channel subfamily M member 7 Homo sapiens
2 The authors developed and optimized a fluorescent dye-based bioassay measuring the fluorescence quench of fura-2 by TRPM7-mediated Mn2+ influx in HEK293 cells that stably overexpress TRPM7. Fura-2 transient receptor potential cation channel subfamily M member 7 Homo sapiens