Title : Central arterial aging and the epidemic of systolic hypertension and atherosclerosis.

Pub. Date : 2007 Sep-Oct

PMID : 20409863






1 Functional Relationships(s)
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1 This profile is proinflammatory, and is manifested by intimal infiltration of fetal cells, increased production of angiotensin II (Ang II)-signaling pathway molecules, eg, matrix metalloproteases (MMPs), and monocyte chemoattractant protein (MCP-1), transforming growth factor B1 (TGF-beta1), enhanced activation of MMPs, TGF-beta, and NADPH oxidase, and reduced nitric oxide (NO) bioavailability. Nitric Oxide angiotensinogen Homo sapiens