Title : Insulin inhibits human erythrocyte cAMP accumulation and ATP release: role of phosphodiesterase 3 and phosphoinositide 3-kinase.

Pub. Date : 2010 Feb

PMID : 20404042






2 Functional Relationships(s)
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1 Insulin inhibits human erythrocyte cAMP accumulation and ATP release: role of phosphodiesterase 3 and phosphoinositide 3-kinase. Cyclic AMP insulin Homo sapiens
2 Here, we investigated the hypothesis that insulin activates PDE3 in human erythrocytes via a PI3K-mediated mechanism resulting in cAMP hydrolysis and inhibition of ATP release. Cyclic AMP insulin Homo sapiens