Title : Activation of human mast cells through the platelet-activating factor receptor.

Pub. Date : 2010 May

PMID : 20392487






3 Functional Relationships(s)
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1 Cell-signaling pathways in PB-derived MCs in response to PAF were investigated by analyzing the effect of various inhibitors and the silencing of phospholipase C (PLC) mRNA on PAF-mediated histamine release. Histamine PCNA clamp associated factor Homo sapiens
2 Cell-signaling pathways in PB-derived MCs in response to PAF were investigated by analyzing the effect of various inhibitors and the silencing of phospholipase C (PLC) mRNA on PAF-mediated histamine release. Histamine PCNA clamp associated factor Homo sapiens
3 RESULTS: We show for the first time that PAF induces histamine release from human lung MCs and PB-derived MCs but not skin MCs. Histamine PCNA clamp associated factor Homo sapiens