Pub. Date : 2010 Mar
PMID : 20388821
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Studies of the toxicological potential of capsinoids, XIII: inhibitory effects of capsaicin and capsinoids on cytochrome P450 3A4 in human liver microsomes. | Capsaicin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 2 | Capsaicin clearly inhibited cytochrome P450 3A4 activity, losing 50% of the activity at 21.5 micromol/L. | Capsaicin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 3 | Preincubation increased the capsaicin inhibitory activity against cytochrome P450 3A4 in a time-dependent manner. | Capsaicin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |
| 4 | Capsaicin was shown to inhibit cytochrome P450 3A4, probably through a mechanism-based inhibition. | Capsaicin | cytochrome P450 family 3 subfamily A member 4 | Homo sapiens |