Title : Interactions between theophylline and salbutamol on cytokine release in human monocytes.

Pub. Date : 2010 Jul

PMID : 20388727






2 Functional Relationships(s)
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1 These results show that beta(2)-agonists have opposing effects on the generation of TNF-alpha and IL-6, but that when they were combined with clinically relevant concentrations of theophylline, theophylline, like dexamethasone, was capable of augmenting the anti-inflammatory effects of the beta(2)-agonists while at the same time preventing their proinflammatory effect. Theophylline potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens
2 These results show that beta(2)-agonists have opposing effects on the generation of TNF-alpha and IL-6, but that when they were combined with clinically relevant concentrations of theophylline, theophylline, like dexamethasone, was capable of augmenting the anti-inflammatory effects of the beta(2)-agonists while at the same time preventing their proinflammatory effect. Theophylline potassium calcium-activated channel subfamily M regulatory beta subunit 2 Homo sapiens