Title : Nicotinic acetylcholine receptors of the dorsal hippocampus and the basolateral amygdala are involved in ethanol-induced conditioned place preference.

Pub. Date : 2010 Jun 30

PMID : 20381593






4 Functional Relationships(s)
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1 Furthermore, microinjection of nicotine (0.5-1 microg/rat) into both CA1 regions (intra-CA1) and the BLA (intra-BLA) did not produce a significant CPP. Nicotine carbonic anhydrase 1 Rattus norvegicus
2 Interestingly, intra-CA1 or -BLA administration of nicotine plus ethanol (0.5 g/kg) during conditioning phase significantly induced a strong CPP. Nicotine carbonic anhydrase 1 Rattus norvegicus
3 However, intra-CA1 or -BLA microinjection of mecamylamine (1-4 microg/rat) reversed the response induced by the microinjection of nicotine (1 microg/rat, intra-CA1 or -BLA) plus ethanol (0.5 g/kg i.p.) Nicotine carbonic anhydrase 1 Rattus norvegicus
4 Moreover, intra-CA1 administration of nicotine plus ethanol increased the locomotor activity on the test day which was reversed by pretreatment with mecamylamine, while other treatments had no effect on locomotor activity. Nicotine carbonic anhydrase 1 Rattus norvegicus