Pub. Date : 2010 Jun
PMID : 20380623
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Deferoxamine mesylate is toxic for retinal pigment epithelium cells in vitro, and its toxicity is mediated by p38. | Deferoxamine | mitogen-activated protein kinase 14 | Homo sapiens |
| 2 | Deferoxamine induces significant cell death in RPE cells, accompanied by phosphorylation of p38 and Erk. | Deferoxamine | mitogen-activated protein kinase 14 | Homo sapiens |
| 3 | In conclusion, deferoxamine is directly toxic on RPE cells, its toxicity depending on p38. | Deferoxamine | mitogen-activated protein kinase 14 | Homo sapiens |