Title : Trs85 directs a Ypt1 GEF, TRAPPIII, to the phagophore to promote autophagy.

Pub. Date : 2010 Apr 27

PMID : 20375281






2 Functional Relationships(s)
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1 The Trs85 subunit of the TRAPPIII complex directs this Ypt1 GEF to the phagophore assembly site (PAS) that is involved in autophagosome formation. Aminosalicylic Acid RAB1A, member RAS oncogene family Homo sapiens
2 Consistent with the observation that a Ypt1 GEF is directed to the PAS, we find that Ypt1 is essential for autophagy. Aminosalicylic Acid RAB1A, member RAS oncogene family Homo sapiens