Title : Noradrenaline acting at beta-adrenoceptors induces expression of IL-1beta and its negative regulators IL-1ra and IL-1RII, and drives an overall anti-inflammatory phenotype in rat cortex.

Pub. Date : 2010 Jul-Aug

PMID : 20361987






2 Functional Relationships(s)
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1 Moreover, administration of the brain penetrant beta(2)-adrenoceptor agonist clenbuterol induced expression of IL-1beta, IL-1ra and IL-1RII in rat brain. Clenbuterol adrenoceptor beta 2 Rattus norvegicus
2 The ability of clenbuterol to activate the IL-1 system was blocked by propranolol, and was mimicked by the highly selective beta(2)-adrenoceptor agonist formoterol. Clenbuterol adrenoceptor beta 2 Rattus norvegicus