Title : Serine 129 phosphorylation reduces the ability of alpha-synuclein to regulate tyrosine hydroxylase and protein phosphatase 2A in vitro and in vivo.

Pub. Date : 2010 Jun 4

PMID : 20356833






1 Functional Relationships(s)
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1 In dopaminergic tissues from mice overexpressing human a-Syn in catecholamine neurons only, TH-Ser-19 and TH-Ser-40 phosphorylation and activity were also reduced, whereas PP2A was more active. Catecholamines synuclein, alpha Mus musculus